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HHMI is a science philanthropy whose mission is to advance basic biomedical research and science education for the benefit of humanity.

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HHMI - Howard Hughes Medical Institute

At the Howard Hughes Medical Institute, we believe in the power of individuals to advance science through research and science education, making discoveries that benefit humanity. Learn more about how we move science forward. Christine Jacobs-Wagner Investigator »
Institute Oct 14 2021
HHMI Expands Commitment to Diversity, Equity, and Inclusion

HHMI is pledging $2 billion to achieve goals that will benefit us all. Learn more about our strategy to influence academic science at key career stages. 

Research May 05 2022
Cutting Calories and Eating at the Right Time of Day Leads to Longer Life in Mice

In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity.

Research Mar 31 2022
Complete Human Genome Deciphered for the First Time

Twenty years after scientists first reported reading the human genome, the Telomere-to-Telomere consortium has now unveiled a complete version. Their work uncovered hundreds of new genes and opens the door to new insights into evolution and disease.

Research Mar 30 2022
Discovery of How Hyaluronic Acid Is Made Could Spur New Therapeutics

For over two decades, scientists have puzzled over how vertebrates make the essential polysaccharide hyaluronic acid, which has broad medical applications. One team took a different tack and solved the mystery.

Research Mar 10 2022
After More than 20 Years, Scientists Have Solved the Full-Length Structure of a Janus Kinase

More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers.

Research Mar 09 2022
When Ribosomes Collide: How Bacteria Clean Up After Molecular Crashes

Tiny cellular machines called ribosomes build proteins. When this building process goes awry in bacteria, ribosomes collide, triggering the arrival of a first responder molecule that begins a rescue operation.

Research Mar 01 2022
Viral Cover-Up: SARS-CoV-2 Cap Offers New Target for Antivirals

Before it can wreak havoc in human cells, the virus that causes COVID-19 must hide the tip of its genetic material. By delving into how the virus puts on this disguise, researchers have identified a unique way to fight it.

Research Feb 23 2022
How Some Gut Microbes Awaken Zombie Viruses in Their Neighbors

Gut bacteria brew all sorts of chemicals, but we don’t know what most of them do. A new study suggests that one such compound, previously linked to cancer, may serve as a bizarre weapon in microbial skirmishes.

Research Feb 08 2022
Nasal Spray Booster Keeps COVID-19 at Bay

In mice, a vaccination strategy that uses an mRNA coronavirus vaccine injection followed by a nasal spray booster generates immune protection in the airways.

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Institute Oct 14 2021
HHMI Expands Commitment to Diversity, Equity, and Inclusion

HHMI is pledging $2 billion to achieve goals that will benefit us all. Learn more about our strategy to influence academic science at key career stages. 

Research May 05 2022
Cutting Calories and Eating at the Right Time of Day Leads to Longer Life in Mice

In a study that followed hundreds of mice over their lifespans, calorie restriction combined with time-restricted eating boosted longevity.

Research Mar 31 2022
Complete Human Genome Deciphered for the First Time

Twenty years after scientists first reported reading the human genome, the Telomere-to-Telomere consortium has now unveiled a complete version. Their work uncovered hundreds of new genes and opens the door to new insights into evolution and disease.

Research Mar 30 2022
Discovery of How Hyaluronic Acid Is Made Could Spur New Therapeutics

For over two decades, scientists have puzzled over how vertebrates make the essential polysaccharide hyaluronic acid, which has broad medical applications. One team took a different tack and solved the mystery.

Research Mar 10 2022
After More than 20 Years, Scientists Have Solved the Full-Length Structure of a Janus Kinase

More than two decades of effort went into a project that has now revealed the structure of a crucial signaling molecule, opening the door to new and better drugs for some cancers.

Research Mar 09 2022
When Ribosomes Collide: How Bacteria Clean Up After Molecular Crashes

Tiny cellular machines called ribosomes build proteins. When this building process goes awry in bacteria, ribosomes collide, triggering the arrival of a first responder molecule that begins a rescue operation.

Research Mar 01 2022
Viral Cover-Up: SARS-CoV-2 Cap Offers New Target for Antivirals

Before it can wreak havoc in human cells, the virus that causes COVID-19 must hide the tip of its genetic material. By delving into how the virus puts on this disguise, researchers have identified a unique way to fight it.

Research Feb 23 2022
How Some Gut Microbes Awaken Zombie Viruses in Their Neighbors

Gut bacteria brew all sorts of chemicals, but we don’t know what most of them do. A new study suggests that one such compound, previously linked to cancer, may serve as a bizarre weapon in microbial skirmishes.

Research Feb 08 2022
Nasal Spray Booster Keeps COVID-19 at Bay

In mice, a vaccination strategy that uses an mRNA coronavirus vaccine injection followed by a nasal spray booster generates immune protection in the airways.

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